APPENDICULAR SKELETAL MUSCLE MASS INDEX AND BONE MINERAL DENSITY OF POSTMENOPAUSE WOMEN
Name: GEISE FERREIRA DA CRUZ
Publication date: 05/05/2021
Advisor:
Name |
Role |
|---|---|
| JOSÉ LUIZ MARQUES ROCHA | Co-advisor * |
| VALDETE REGINA GUANDALINI | Advisor * |
Examining board:
| Name |
Role |
|---|---|
| CAROLINA PERIM DE FARIA | Internal Alternate * |
| GLENDA BLASER PETARLI | External Alternate * |
| JOSÉ LUIZ MARQUES ROCHA | Co advisor * |
| LUCIANE BRESCIANI SALAROLI | Internal Examiner * |
| VALDETE REGINA GUANDALINI | Advisor * |
Summary: The appendicular skeletal muscle mass index (ASMMI) is the main parameter to identify low muscle mass and has been considered an important risk indicator for osteoporosis. Early identification of low ASMMI is essential to prevent negative outcomes such as sarcopenia, falls and functional disability. This makes the study of ASMMI and its relationship with bone mineral density (BMD) relevant, aiming at providing early diagnoses and interventions with
consequent improvement in the health and quality of life of postmenopausal
women. Therefore, the objective of this study was to verify the association
between ASMMI with the clinical profile, nutritional status and lifestyle of
postmenopausal women and also investigate the relationship between ASMMI and the bone mineral density (BMD) categories of postmenopausal women. For this, a cross-sectional observational study was carried out with a probabilistic
sample. Sociodemographic, clinical, lifestyle, level of physical activity,
biochemical, and anthropometric variables were collected. ASMMI and DMO were measured by dual energy x-ray absorptiometry (DXA). The data were analyzed using the SPSS statistical program, version 22. Fisher's exact test,
Pearson's chi-square test, and multivariate logistic regression were applied
for data analysis. 114 postmenopausal women between 60 and 69.9 years of age were analyzed, with a predominance of non-white race / color, menopause time less than or equal to 19 years, with less than 4 years of study, who never
smoked or consumed alcohol. Most women were classified as active enough, with 1 to 3 comorbidities, using calcium supplementation and undergoing regular sun exposure. The body mass index, calf perimeter and the thickness of the adductor pollicis muscle, were positively associated with ASMMI, presenting themselves as protective factors for muscle mass. ASMMI was not associated with the BMD categories of postmenopausal women, however, advanced age, longer menopause time, low weight, adequate waist circumference and lower averages of ASMMI were more present among postmenopausal women with osteoporosis. In conclusion, this study demonstrated that conventional anthropometric parameters positively influenced the ASMMI, while the BMD categories did not remain associated with the ASMMI after adjustments for confounding variables.
