Alcohol consumption and dyslipidemias in participants of the Longitudinal Study of Adult Health (ELSA-BRASIL)
Name: OSCAR GEOVANNY ENRIQUEZ MARTINEZ
Type: MSc dissertation
Publication date: 06/04/2018
Advisor:
Name |
Role |
|---|---|
| MARIA DEL CARMEN BISI MOLINA | Advisor * |
Examining board:
| Name |
Role |
|---|---|
| CAROLINA PERIM DE FARIA | Internal Examiner * |
| MARIA DEL CARMEN BISI MOLINA | Advisor * |
Summary: Dyslipidemias are defined as a change in the functioning of lipoproteins, such as total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides. Several factors are involved in its mechanisms, among which alcohol consumption. Thisis increasing in all. In Brazil, alcohol abuse increased by 3.4% in 10 years. The objective of this study was to investigate the relationship between alcohol consumption, as well as the type of alcoholic beverage, and lipid parameters in ELSA-Brasil participants. A total of 9,548 participants, aged 35-74 years, of both sexes were studied. Socio-demographic, lifestyle, biochemical and anthropometric data were collected in a standardized way in six teaching or research institutions. The consumption of alcoholic beverages was categorized in terms of consumption (low, medium, high), in mL of pure alcohol / week. Linear regression models were performed for each type and total alcoholic beverages. The prevalence of altered lipid parameters in this study was 64.9%, 29.2%, 62% and 84% for total cholesterol, triglycerides, HDL cholesterol and LDL cholesterol, respectively. Beer was the most consumed type of drink (38.0%), wine followed (24.9%) and liquor (11.5%). An increase in all lipid parameters was observed with the exception of LDL cholesterol. In the analysis by type of beverage, it was observed. that total cholesterol is associated with the consumption of beer and liquor (high consumption), the triglycerides are associated with medium and high consumption of beer, but decrease with medium and high consumption, and HDL-c increases with beer consumption and with the medium and high consumption of wine and liquors. We conclude that relationship between total alcohol consumption and the concentrations of TC and HDL-c in the sample studied. Alcohol consumption increased the biochemical parameters evaluated, with the exception of LDL-c.
