Association between weight gain and insulin use in women with gestational diabetes mellitus
Name: PATRÍCIA STHEL CAIADO VENTORIM
Publication date: 11/09/2024
Examining board:
Name |
Role |
|---|---|
| FABIANA DE CASSIA CARVALHO OLIVEIRA | Examinador Interno |
| JOSE LUIZ MARQUES ROCHA | Coorientador |
| KARINA DOS SANTOS | Examinador Externo |
| MIRIAM CARMO RODRIGUES BARBOSA | Presidente |
Summary: Objective: The present study investigated the relationship between insulin use (UI), pre-pregnancy nutritional status (PNS) and maternal weight gain (WG) during pregnancy in women with Gestational Diabetes Mellitus (GDM). Methods: Retrospective cross-sectional study (2017-2022) with secondary data from women with GDM treated at a University Hospital in southeastern Brazil. The suitability of the GP was assessed according to new curves for Brazilian pregnant women. ENP, age, height, color, education, marital status, location, parity, pregnancies, abortions, fasting blood glucose and hypertensive disorders were also evaluated. Multiple logistic regression was used to verify the association of the dependent variable UI with variables related to the development of GDM. Results: Among the 355 participants, 48.7% were classified as obese and 47.4% used insulin. Volunteers with obesity before pregnancy were more likely to use insulin (OR 2.26; 95% CI: 1.16-4.41; p=0.003) than eutrophic pregnant women. In the same sense, pregnant women who were eutrophic before pregnancy, but who had a GP above the recommended level, were more likely to use insulin (OR 3.22; 95%CI:1.15-9.05; p=0.024). On the other hand, when the analysis was carried out within the group that had adequate or less than adequate GP, obese pregnant women were more likely to use insulin (OR 4.33; 95% CI:1.76-10.6;p= 0.001). The results reinforce the importance of nutritional care both for adjusting pre-pregnancy weight and for gestational weight loss. Thus highlighting the need for the development of specific GP guidelines for women with GDM.
