Name: FABIANE FARINA
Publication date: 03/12/2021
Advisor:
Name |
Role |
|---|---|
| FABIANO KENJI HARAGUCHI | Co-advisor * |
| ROGERIO GRACA PEDROSA | Advisor * |
Examining board:
| Name |
Role |
|---|---|
| FABIANO KENJI HARAGUCHI | Co advisor * |
| LUCIANE BRESCIANI SALAROLI | Internal Alternate * |
| NAZARE SOUZA BISSOLI | External Alternate * |
| ROGERIO GRACA PEDROSA | Advisor * |
| VALDETE REGINA GUANDALINI | Internal Examiner * |
Summary: Bariatric surgery (BC) has been considered the recommended treatment for severe obesity, as it has shown satisfactory results in the reduction of weight and associated comorbidities. Weight loss resulting from BC, mainly due to reduction of fat mass (FM), implies changes in body composition, which is directly related to improvements in comorbidities. However, some individuals cannot achieve the desired weight loss with this procedure, which can influence the metabolic effects of BC and limit the expected health benefits. Therefore, this study investigated the association of body composition indices measured in the preoperative period with the percentage of excess weight loss (%EWL) in women undergoing BC with the Roux-en-Y intestinal bypass technique. The group was evaluated at four times: preoperatively (approximately 30 days before surgery) (T0), approximately three months after surgery (T1), approximately six months after surgery (T2) and approximately twelve months after surgery (T3). The weight reduction was 36.4±9.4 kg (T3), equivalent to %EWL of 83.9±24.5%. In the same period, the body mass index (BMI), the fat mass index (FMI), the lean mass index (LMI), the skeletal muscle mass index (SMMI) and the body cell mass index (BCMI) reduced by 35.6%, 48.4%, 23.0%, 7.7%, and by 25.4%, respectively. The phase angle (PhA) reduced at T1 (-17.1%) and did not show further change. Negative association of %EWL with BMI and FMI was found (moderate correlation in T1 and strong correlation in T2 and T3). Similarly, negative association was observed between %EWL and LMI (moderate correlation at T1 and T3 and strong correlation at T2). There was no association between preoperative PhA and %EWL in any of the evaluated moments. The present study showed that preoperative BMI, FMI and LMI were the best predictors of %EWL at T1, T2 and T3.
